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Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and S(N)1 chemotherapeutic agents

Side effects of baclofen include sleepiness, dizziness, nausea, headache, and confusion

Oral TB-500 is not a clinically valid delivery route: the peptide cannot survive the gastrointestinal tract intact in a way that produces systemic effects comparable to subcutaneous injection

A polymer micelle (CAT/CPT-TPP/PEG-Ce6, CTC) achieves triple-synergistic amplification of ROS via PDT and chemotherapy, inducing immunogenic cell death

Focusing on the nervous system, several studies highlight how metabolic alterations due to VitB12 deficiency can trigger molecular/cellular changes, such as the accumulation of oxidative stress, epigenetic modifications, modulation of gene expression or protein content, or alterations in lysosomal activity

Methylene blue is promoted for increasing energy, slowing aging, and improving memory